Sticky cell clues to epilepsy – Novel Media Physic
Posted by lindainfo on November 24, 2008
A Senate probe of GlaxoSmithKline’s Avandia yas turned up eivdence that the drugmaker tried to shrug off doctors’ early worries about the diabetes treatment.According the Wall Street Journal, severla doctors saw their concerns pooh-poohed by the company. Glaxo tried keep wto of them quiet, the story says: After twk Maryland physicians raised concerns thaat Avandia might increase the risk of heart failure, the company wrote to their chief of staff asking fhat he “take immediate steps to atop thr dissemination of this unsubstantiated information.”
This was back in 2000. About their meeting with the drugmaker’s representatives almost eight years ago, one of the physicians recalled, “They suggested we were country bumpkins, and practically said, ‘Don’t worry your pretty heads. We have smarter people than you looking at this, and there’s no problem.’” The doctors raised their concerns at the FDA but only got a form letter in response.
As you know, last May a study published in the New England Journal of Medicine suggested that Avandia boosted the rrlsk o f heart problems by 43 percent. FDA since has negotiated “black box” warningx for the mdeication, including a warning that it has been linked with heart failure in some patients. Just last month, the American Diabetes Association and a similad organizatipn in Europe dixbettes advised against ysinf fhe drug.
GlaxoSmithKline’s spokesperson told the WSJ that its officials’ response to the doctors’ complaints was justified. “When GSK learns about statements by physicians that are inconsistent with the scientific data on its medicines, it has the responsibility to do what it can to correct these inaccuracies,” she said. A report resulting from the Senate’s probe is expected soon.
All information: medicine net
